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CMT Australia

How do MORC2 mutations contribute to CMT?

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Crystal Bruton


201 days ago

Lisa Moore


232 days ago

The Walter and Eliza Hall Institute is pleased to partner with CMT Australia's research objectives to better understand how MORC2 mutations contribute to Charcot-Marie-Tooth (CMT) disease.

Charcot-Marie-Tooth (CMT) is a genetic condition associated with profound muscular weakness, typically becoming noticeable in children and young adults. More than 80 genes have been identified in CMT, with each gene linked to one or more types of the disease. The level of disability varies from mild to severe.

This project focuses on CMT caused by the MORC2 gene, where there is more severe muscle weakness. These patients have an early onset, sometimes as young as two or three, with loss of sensation in the hands and feet, causing major difficulties in patients' daily lives. Recent development at the Institute has opened up exciting opportunities to make significant advances in this area.

CMT Australia has kicked off this project with seed funding of $10,000. This CrowdRaiser seeks to raise the balance of project funding requested of CMT Australia of $10,000 so we can help deliver the outcomes over the two-year term of the project.

We invite your support as either a participant or a financial partner. We would also be grateful if you could share the link to this CrowdRaiser page with your friends and family. The more people who can help, the better!

Thank you


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PO Box 493


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